Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415862 | 0.85 | DHODH (0.47) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL9415878 | 0.84 | GAA (0.43) | DHODHGAACYP19A1LMNACYP3A4 | |
| SCHEMBL9415887 | 0.84 | DHODH (0.43) | DHODHGAACYP19A1LMNACYP3A4 | |
| SCHEMBL9059091 | 0.84 | DHODH (0.44) | DHODHLMNAKDM4ENPSR1MAPT | |
| SCHEMBL9415886 | 0.83 | DHODH (0.44) | DHODHGAACYP19A1CYP3A4CYP2D6 | |
| SCHEMBL9415889 | 0.75 | DHODH (0.43) | DHODHLMNAKDM4ENPSR1MEN1 | |
| SCHEMBL8123710 | 0.74 | MEN1 (0.46) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL8123707 | 0.74 | MEN1 (0.46) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL20912581 | 0.73 | MEN1 (0.45) | DHODHGAALMNACYP3A4CYP2D6 | |
| SCHEMBL20912579 | 0.73 | MEN1 (0.45) | DHODHGAALMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |