Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415871 | 0.91 | DHODH (0.41) | EGFRERBB2DHODHS1PR1HDAC1 | |
| SCHEMBL9415886 | 0.83 | DHODH (0.44) | EGFRERBB2DHODHS1PR1HDAC1 | |
| SCHEMBL8802130 | 0.78 | NPSR1 (0.44) | DHODHS1PR1HDAC1HDAC6MAPT | |
| SCHEMBL9415881 | 0.77 | DHODH (0.41) | EGFRERBB2DHODHMAPTNPSR1 | |
| SCHEMBL9415889 | 0.76 | DHODH (0.43) | DHODHHDAC1HDAC6MAPTNPSR1 | |
| SCHEMBL9059091 | 0.75 | DHODH (0.44) | DHODHS1PR1HDAC1HDAC6MAPT | |
| SCHEMBL9056464 | 0.74 | DHODH (0.45) | EGFRERBB2DHODHMAPTNPSR1 | |
| SCHEMBL9057497 | 0.71 | DHODH (0.38) | EGFRERBB2DHODHS1PR1HDAC1 | |
| SCHEMBL9415865 | 0.69 | DHODH (0.49) | EGFRERBB2DHODHMAPTNPSR1 | |
| SCHEMBL9415877 | 0.68 | DHODH (0.44) | DHODHMAPTNPSR1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |