Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415869 | 0.91 | EGFR (0.41) | DHODHNPSR1MAPTEGFRERBB2 | |
| SCHEMBL9415881 | 0.85 | DHODH (0.41) | DHODHNPSR1MAPTEGFRERBB2 | |
| SCHEMBL8802130 | 0.85 | NPSR1 (0.44) | DHODHNPSR1MAPTHDAC1HDAC6 | |
| SCHEMBL9056464 | 0.83 | DHODH (0.45) | DHODHNPSR1MAPTEGFRERBB2 | |
| SCHEMBL9415889 | 0.82 | DHODH (0.43) | DHODHNPSR1MAPTHDAC1HDAC6 | |
| SCHEMBL9059091 | 0.82 | DHODH (0.44) | DHODHNPSR1MAPTHDAC1HDAC6 | |
| SCHEMBL9057497 | 0.78 | DHODH (0.38) | DHODHNPSR1MAPTEGFRERBB2 | |
| SCHEMBL9415886 | 0.73 | DHODH (0.44) | DHODHNPSR1MAPTEGFRERBB2 | |
| SCHEMBL8801560 | 0.71 | NPSR1 (0.39) | DHODHNPSR1MAPTKDM4ERECQL | |
| SCHEMBL7842408 | 0.70 | DHODH (0.51) | DHODHNPSR1MAPTEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |