Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416279 | 1.00 | BCHE (0.47) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL10514784 | 0.86 | TSHR (0.45) | BCHEACHEPDE4DTSHRTAAR1 | |
| SCHEMBL9369568 | 0.86 | TSHR (0.45) | BCHEACHEPDE4DTSHRTAAR1 | |
| SCHEMBL9366165 | 0.86 | TSHR (0.45) | BCHEACHEPDE4DTSHRTAAR1 | |
| SCHEMBL10517771 | 0.86 | TSHR (0.45) | BCHEACHEPDE4DTSHRTAAR1 | |
| SCHEMBL9416326 | 0.81 | PDE4D (0.41) | PDE4DGJB2TSHRTAAR1LMNA | |
| SCHEMBL9416327 | 0.81 | PDE4D (0.41) | PDE4DGJB2TSHRTAAR1LMNA | |
| SCHEMBL21783255 | 0.80 | BCHE (0.50) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL2531282 | 0.77 | BCHE (0.47) | BCHEACHEPDE4DHTR1ATSHR | |
| SCHEMBL8781390 | 0.77 | BCHE (0.47) | BCHEACHEPDE4DHTR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630897-A2 | 3-Hydroxy-4-hydroxymethyl-2-methylene-cyclopentyl purines and pyrimidines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |