Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482146 | 0.86 | SMN1; SMN2 (0.59) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL4909832 | 0.79 | HTT (0.47) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL13440739 | 0.75 | ABL1 (0.50) | MEN1KMT2APOLB | |
| SCHEMBL13440743 | 0.74 | MEN1 (0.43) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL28282789 | 0.73 | HPGD (0.53) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL14132985 | 0.73 | TP53 (0.74) | MEN1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL11706158 | 0.72 | MEN1 (0.53) | MEN1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL4520789 | 0.70 | GRM5 (0.63) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL27728861 | 0.70 | KMT2A (0.51) | MEN1KMT2AGAASMN1; SMN2HPGD | |
| SCHEMBL13827695 | 0.70 | GAA (0.57) | MEN1KMT2AGAASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627423-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE AND AGROHORTICULTURAL BACTERICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |