Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133462 | 0.83 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL3504748 | 0.83 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL11743606 | 0.83 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL8791190 | 0.81 | KMT2A (0.71) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL3504123 | 0.81 | KMT2A (0.60) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL3507895 | 0.80 | DPP8 (0.57) | KMT2ANPC1ABCB1ABCC1CA2 | |
| SCHEMBL9416670 | 0.80 | MAPK1 (0.77) | KMT2ACA2CA9ALDH1A1KDM4E | |
| SCHEMBL8790957 | 0.80 | KMT2A (0.68) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL5096699 | 0.79 | KMT2A (0.86) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL9669207 | 0.79 | MAPK1 (0.56) | KMT2ANPC1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |