Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | WDR5 | P61964 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.57 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495972 | 0.92 | HSD17B2 (0.83) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL12687956 | 0.91 | HSD17B2 (0.66) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL9416624 | 0.90 | KMT2A (0.89) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL12496881 | 0.90 | HSD17B2 (0.80) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL15485186 | 0.88 | HSD17B2 (0.82) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL12688091 | 0.87 | HSD17B2 (0.62) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL12688033 | 0.86 | HSD17B2 (0.75) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL12495934 | 0.85 | HSD17B2 (1.00) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL21425705 | 0.83 | MEN1 (0.60) | HSD17B2KMT2AMEN1POLBHPGD | |
| SCHEMBL6417242 | 0.83 | HSD17B2 (0.63) | HSD17B2KMT2AMEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |