Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.89 |
| ▸ | MEN1 | O00255 | 3/20 | 0.89 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416583 | 0.90 | HSD17B2 (0.74) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL18773942 | 0.89 | KMT2A (0.84) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL15676804 | 0.88 | KMT2A (0.82) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL10268983 | 0.85 | KMT2A (0.78) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL9416641 | 0.85 | MEN1 (0.77) | KMT2AMEN1HSD17B2MAPK1HTT | |
| SCHEMBL18970229 | 0.84 | KMT2A (0.76) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL1691692 | 0.84 | KMT2A (0.76) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL15485186 | 0.84 | HSD17B2 (0.82) | KMT2AMEN1HSD17B2POLBHPGD | |
| SCHEMBL9416561 | 0.83 | TSHR (0.64) | KMT2AMEN1HPGDL3MBTL1MAPT | |
| SCHEMBL12495972 | 0.82 | HSD17B2 (0.83) | KMT2AMEN1HSD17B2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |