Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 4/20 | 0.59 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134127 | 0.93 | CHRM2 (0.74) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL8880839 | 0.91 | KDM4E (0.77) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL30245831 | 0.91 | KDM4E (0.77) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL6122475 | 0.91 | CHRM2 (0.72) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL7245167 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL24343795 | 0.85 | ALDH1A1 (0.61) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL18635836 | 0.85 | HDAC1 (0.68) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL4916089 | 0.85 | CHRM2 (0.81) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL1279045 | 0.85 | HTT (0.73) | KDM4EALDH1A1HTTSMN1; SMN2CHRM2 | |
| SCHEMBL121529 | 0.84 | CHRM2 (0.70) | KDM4EALDH1A1HTTSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |