Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648537 | 0.83 | TAAR1 (0.61) | TSHRNFKB1CYP3A4LMNATAAR1 | |
| SCHEMBL30873093 | 0.83 | TUBB4A (0.75) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL27183302 | 0.83 | TUBB4A (0.75) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL15042812 | 0.83 | TUBB4A (0.75) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL29442255 | 0.83 | TUBB4A (0.75) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL3691695 | 0.83 | CYP1A2 (0.59) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL9416555 | 0.82 | TSHR (0.54) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL27777910 | 0.81 | TSHR (0.62) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL10049174 | 0.80 | CYP1A2 (0.60) | TSHRNFKB1CYP1A2CYP3A4MEN1 | |
| SCHEMBL13131818 | 0.80 | TAAR1 (0.61) | TSHRNFKB1CYP3A4LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |