Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416860 | 0.98 | MAPT (0.47) | TEKMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10626101 | 0.95 | MAPT (0.49) | TEKMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10709310 | 0.92 | MAPT (0.46) | TEKMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9416700 | 0.83 | TEK (0.53) | TEKMAPTALDH1A1GAAHPGD | |
| SCHEMBL9416868 | 0.83 | MAPT (0.52) | TEKMAPTALDH1A1GAAHPGD | |
| SCHEMBL10627105 | 0.83 | MAPK1 (0.46) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL10631144 | 0.83 | MAPT (0.48) | MAPTALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL10630997 | 0.82 | MAPT (0.45) | TEKMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10631449 | 0.81 | NPC1 (0.46) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL26699450 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1GAASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0262209-A1 | SYNERGISTIC PLANT GROWTH REGULATOR COMPOSITIONS. | RHONE POULENC BV (NL) | 1988-04-06 | — | — | EP | disclosed |
| US-4736056-A | Process for the production of malonic acid derivative compounds | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC., T.W. ALEXANDER DR., RESEARCH TRIANGLE PARK, NC. A CORP. OF PA. | 1988-04-05 | — | — | US | disclosed |
| WO-1987005781-A2 | SYNERGISTIC PLANT GROWTH REGULATOR COMPOSITIONS | RHONE-POULENC NEDERLANDS B.V. (NL) | 1987-10-08 | — | — | WO | disclosed |