Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416950 | 0.91 | KDM4E (0.43) | MAPTGAAHTTLMNATDP1 | |
| SCHEMBL16119871 | 0.81 | MAPT (0.52) | CYP2A13MAPTCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL18161774 | 0.81 | MAPT (0.52) | CYP2A13MAPTCYP2C9GAAERN1 | |
| SCHEMBL16119872 | 0.81 | MAPT (0.52) | CYP2A13MAPTCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL9417035 | 0.80 | MAPT (0.44) | CYP2A13MAPTCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL28326950 | 0.80 | MAPT (0.64) | CYP2A13MAPTCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11279318 | 0.74 | MAPT (0.59) | CYP2A13MAPTCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL20143467 | 0.74 | MAPT (0.45) | MAPTCYP2C9GAANPSR1LMNA | |
| SCHEMBL18161772 | 0.74 | MAPT (0.45) | MAPTCYP2C9GAANPSR1LMNA | |
| SCHEMBL9417077 | 0.73 | PTGS1 (0.39) | MAPTCYP2D6GAAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |