SCHEMBL20143467

SCHEMBL20143467

Cc1cc(CN2CCOCC2)cc(/C=N/C2CCCC[C@H]2/N=C/c2cc(CN3CCOCC3)cc(C)c2O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.40
BRD4 O60885 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NOS1 P29475 2/20 0.38
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
KDM4E B2RXH2 1/20 0.37
KMT2A Q03164 3/20 0.37
HSD17B10 Q99714 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CNR2 P34972 4/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18161772 1.00 MAPT (0.45) MAPTL3MBTL1BRD4LMNAGAA
SCHEMBL16119873 0.91 MAPT (0.43) MAPTL3MBTL1BRD4LMNAGAA
SCHEMBL18161783 0.88 CYP2C9 (0.43) MAPTL3MBTL1LMNAGAAMAPK1
SCHEMBL20462859 0.88 CYP2C9 (0.43) MAPTL3MBTL1LMNAGAAMAPK1
SCHEMBL18161779 0.82 SIGMAR1 (0.38) MAPTLMNAGAAMAPK1KDM4E
SCHEMBL20462847 0.82 SIGMAR1 (0.38) MAPTLMNAGAAMAPK1KDM4E
SCHEMBL18161774 0.79 MAPT (0.52) MAPTL3MBTL1BRD4LMNAGAA
SCHEMBL16119871 0.79 MAPT (0.52) MAPTL3MBTL1BRD4LMNAGAA
SCHEMBL16119872 0.79 MAPT (0.52) MAPTL3MBTL1BRD4LMNAGAA
SCHEMBL20143468 0.78 L3MBTL1 (0.36) L3MBTL1GAAMAPK1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180223042-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SK INNOVATION CO., LTD. (KR) 2018-08-09 US disclosed
US-9969842-B2 Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex SK INNOVATION CO., LTD. (KR) 2018-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180223042-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SMARCC2, SMARCC1, CLNS1A MAPT 4726/4885L3MBTL1 4884/4885BRD4 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.