Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417188 | 0.98 | ESR1 (0.53) | ESR1HSD17B3TTRHPGDTDP1 | |
| SCHEMBL10355978 | 0.85 | ESR1 (0.57) | ESR1HSD17B3TTRALDH1A1MEN1 | |
| SCHEMBL10355766 | 0.84 | HSD17B3 (0.57) | ESR1HSD17B3TTRALDH1A1MEN1 | |
| SCHEMBL6808373 | 0.82 | TTR (0.56) | ESR1TTRTDP1ALDH1A1TSHR | |
| SCHEMBL11741738 | 0.78 | TTR (0.57) | ESR1TTRHPGDALDH1A1TSHR | |
| SCHEMBL2239062 | 0.78 | HSP90AA1 (0.58) | HSD17B3HPGDTDP1ALDH1A1TSHR | |
| SCHEMBL20207163 | 0.78 | HSD17B3 (0.55) | ESR1HSD17B3HPGDTDP1ALDH1A1 | |
| SCHEMBL11740673 | 0.78 | ESR1 (0.49) | ESR1TTRHPGDTDP1ALDH1A1 | |
| SCHEMBL634176 | 0.77 | HSD17B3 (0.55) | HSD17B3HPGDTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL9575803 | 0.77 | HSD17B3 (0.42) | ESR1HSD17B3HPGDTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5227291-A | METHOD FOR DETERMINATION OF ACID PHOSPHATASE ACTIVITY USING 4-ACYL-2, 6-DIHALOPHENYL PHOSPHORIC ACID DERIVATIVES | NITTO BOSEKI CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |