Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417149 | 0.79 | ALDH1A1 (0.41) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA | |
| SCHEMBL9417188 | 0.78 | ESR1 (0.53) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA | |
| SCHEMBL9417154 | 0.77 | ESR1 (0.51) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA | |
| SCHEMBL634176 | 0.73 | HSD17B3 (0.55) | HSD17B3HPGDSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL22013287 | 0.71 | HSD17B3 (0.47) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2239062 | 0.70 | HSP90AA1 (0.58) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA | |
| SCHEMBL9417191 | 0.69 | THRA (0.46) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA | |
| SCHEMBL7436605 | 0.69 | HPGD (0.52) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11568404 | 0.68 | ALDH1A1 (0.43) | HPGDALDH1A1TSHRRECQLHSD17B10 | |
| SCHEMBL19137592 | 0.68 | HSD17B3 (0.44) | HSD17B3HPGDSMN1; SMN2L3MBTL1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227291-A | METHOD FOR DETERMINATION OF ACID PHOSPHATASE ACTIVITY USING 4-ACYL-2, 6-DIHALOPHENYL PHOSPHORIC ACID DERIVATIVES | NITTO BOSEKI CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |