Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PNP | P00491 | 5/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857621 | 0.94 | MEN1 (0.44) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL27503506 | 0.80 | PNP (0.53) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL15643286 | 0.80 | MEN1 (0.58) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL8781788 | 0.79 | PNP (0.64) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL28297087 | 0.76 | PNP (0.51) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL4242268 | 0.76 | TK1 (0.62) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL9417161 | 0.75 | POLB (0.59) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL9417165 | 0.75 | MEN1 (0.44) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL8742556 | 0.74 | MEN1 (0.48) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL9417134 | 0.74 | PNP (0.51) | MEN1KMT2APNPBLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | claimed |