⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL21465023 | 0.95 | — | — | |
| SCHEMBL14790911 | 0.95 | KDM4E (0.32) | — | |
| SCHEMBL14163361 | 0.95 | KDM4E (0.32) | — | |
| Bromide SCHEMBL11709582 | 0.95 | — | — | |
| Iodide SCHEMBL21465022 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL30301523 | 0.95 | — | — | |
| SCHEMBL34886 | 0.84 | — | — | |
| SCHEMBL2857671 | 0.80 | — | — | |
| SCHEMBL8504637 | 0.80 | KDM4E (0.33) | — | |
| Fluoride Ion SCHEMBL1996392 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3096754-B1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-08-29 | — | — | EP | claimed |
| US-9708336-B2 | Metallo-beta-lactamase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-07-18 | — | — | US | claimed |
| EP-3096754-A1 | METALLO-BETA-LACTAMASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-11-30 | — | — | EP | claimed |
| US-20160333021-A1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-11-17 | — | — | US | claimed |
| WO-2015112441-A1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-07-30 | — | — | WO | claimed |
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| EP-3096754-B1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3313832-A1 | 3-TETRAZOLYL-BENZENE-1,2-DISULFONAMIDE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9708336-B2 | Metallo-beta-lactamase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-07-18 | — | — | US | disclosed |
| WO-2016210215-A1 | 3-TETRAZOLYL-BENZENE-1,2-DISULFONAMIDE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-12-29 | — | — | WO | disclosed |
| EP-3096754-A1 | METALLO-BETA-LACTAMASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-11-30 | — | — | EP | disclosed |
| US-20160333021-A1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-11-17 | — | — | US | disclosed |
| EP-0022735-B1 | PROCESS FOR THE PREPARATION OF ACETALDEHYDE | RHONE-POULENC CHIMIE DE BASE (FR) | 1982-04-28 | — | — | EP | disclosed |
| US-4324927-A | Process for the homologization of methanol | RHONE-POULENC INDUSTRIES (FR) | 1982-04-13 | — | — | US | disclosed |
| EP-0046129-A1 | Process for the hydrocarbonylation and/or carbonylation of alkyl carboxylates | RHONE-POULENC CHIMIE DE BASE (FR) | 1982-02-17 | — | — | EP | disclosed |
| EP-0046128-A1 | Process for the hydrocarbonylation and/or carbonylation of alkyl carboxylates | RHONE-POULENC CHIMIE DE BASE (FR) | 1982-02-17 | — | — | EP | disclosed |
| US-4306091-A | CATALYTIC HYDROCARBONYLATION OF METHANOL IN THE PRESENCE OF COBALT, RUTHENIUM AND AN ALKYL HALIDE AND AN IONIC HALIDE | RHONE-POULENC INDUSTRIES (FR) | 1981-12-15 | — | — | US | disclosed |
| EP-0031784-A2 | Process for preparing ethyl carboxylates from their lower homologues | RHONE-POULENC CHIMIE DE BASE (FR) | 1981-07-08 | — | — | EP | disclosed |
| EP-0022735-A1 | Process for the preparation of acetaldehyde | RHONE-POULENC CHIMIE DE BASE (FR) | 1981-01-21 | — | — | EP | disclosed |
| EP-0022038-A1 | Process for the homologation of methanol | RHONE-POULENC CHIMIE DE BASE (FR) | 1981-01-07 | — | — | EP | disclosed |