Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733362 | 0.99 | KDM4E (0.46) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417874 | 0.99 | KDM4E (0.46) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417900 | 0.99 | KDM4E (0.46) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417760 | 0.91 | KDM4E (0.50) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417943 | 0.90 | PTGDR (0.47) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417845 | 0.88 | CNR2 (0.50) | KDM4ELMNAL3MBTL1MAPK1THRB | |
| SCHEMBL9417984 | 0.88 | CNR2 (0.53) | KDM4ELMNAL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL9734673 | 0.88 | PTGDR (0.45) | KDM4ELMNAL3MBTL1MAPK1PTGDR | |
| SCHEMBL9417815 | 0.87 | PLA2G2D (0.51) | L3MBTL1MAPK1ALDH1A1THRBCNR2 | |
| SCHEMBL9417954 | 0.87 | PLA2G2D (0.51) | L3MBTL1MAPK1ALDH1A1THRBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |