Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 8/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 7/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417815 | 1.00 | PLA2G2D (0.51) | PLA2G2DTHRACNR2MAPK1L3MBTL1 | |
| SCHEMBL9417820 | 1.00 | PLA2G2D (0.51) | PLA2G2DTHRACNR2MAPK1L3MBTL1 | |
| SCHEMBL9417845 | 0.99 | CNR2 (0.50) | PLA2G2DTHRACNR2MAPK1L3MBTL1 | |
| SCHEMBL9417984 | 0.96 | CNR2 (0.53) | PLA2G2DTHRACNR2MAPK1L3MBTL1 | |
| SCHEMBL9417874 | 0.89 | KDM4E (0.46) | CNR2MAPK1L3MBTL1THRBALDH1A1 | |
| SCHEMBL9733362 | 0.89 | KDM4E (0.46) | CNR2MAPK1L3MBTL1THRBALDH1A1 | |
| SCHEMBL9417900 | 0.89 | KDM4E (0.46) | CNR2MAPK1L3MBTL1THRBALDH1A1 | |
| SCHEMBL9417760 | 0.88 | KDM4E (0.50) | CNR2MAPK1L3MBTL1THRBALDH1A1 | |
| SCHEMBL9417943 | 0.87 | PTGDR (0.47) | MAPK1L3MBTL1THRBALDH1A1 | |
| SCHEMBL9417839 | 0.87 | KDM4E (0.46) | CNR2MAPK1L3MBTL1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |