Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417942 | 0.91 | LTB4R (0.47) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417817 | 0.88 | NR1H4 (0.52) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417812 | 0.88 | NR1H4 (0.52) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417950 | 0.88 | NR1H4 (0.52) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9734667 | 0.87 | HTT (0.44) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417895 | 0.86 | LTB4R (0.46) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9733359 | 0.86 | LTB4R (0.46) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417860 | 0.86 | LTB4R (0.45) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417873 | 0.86 | LTB4R (0.46) | LTB4RLTB4R2NR1H4MEN1CYP3A4 | |
| SCHEMBL9417840 | 0.86 | NR1H4 (0.50) | LTB4RLTB4R2NR1H4MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |