Vinyl Chloride

Vinyl Chloride

SCHEMBL9418741

C=CCl.CCC(C(=O)O)=C(CC)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.42
FFAR3 O14843 1/20 0.38
GRIK1 P39086 1/20 0.34
GRIA4 P48058 1/20 0.34
GRIK3 Q13003 1/20 0.34
GRIK5 Q16478 1/20 0.34
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinyl Chloride SCHEMBL11423821 1.00 ALDH1A1 (0.42) ALDH1A1TSHRFFAR3GRIK1GRIA4
Vinyl Chloride SCHEMBL6129199 1.00 ALDH1A1 (0.42) ALDH1A1TSHRFFAR3GRIK1GRIA4
SCHEMBL101165 0.83 FFAR3 (0.53) ALDH1A1TSHRFFAR3GRIK1GRIA4
SCHEMBL42603 0.83 FFAR3 (0.53) ALDH1A1TSHRFFAR3GRIK1GRIA4
SCHEMBL42601 0.83 FFAR3 (0.53) ALDH1A1TSHRFFAR3GRIK1GRIA4
Propionic Acid SCHEMBL8983648 0.80
SCHEMBL9860955 0.80 ALDH1A1 (0.39) ALDH1A1TSHRFFAR3GRIK1GRIA4
SCHEMBL11335133 0.80 ALDH1A1 (0.48) ALDH1A1TSHRFFAR3GRIK1GRIA4
SCHEMBL11335137 0.80 ALDH1A1 (0.48) ALDH1A1TSHRFFAR3GRIK1GRIA4
Hydrochloric Acid SCHEMBL9622192 0.80 FFAR3 (0.50) ALDH1A1TSHRFFAR3GRIK1GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1972678-B Steroid intraocular implants with extended sustained release over 2 months ALLERGAN INC 2012-02-29 CN disclosed
CN-1972678-A Steroid intraocular implants with extended sustained release over 2 months ALLERGAN INC (US) 2007-05-30 CN disclosed
EP-0406349-B1 IMPROVED STABILIZERS FOR HALOGEN-CONTAINING POLYMERS ATOCHEM NORTH AMERICA (US) 1994-12-21 EP disclosed
EP-0182526-B1 STABILIZERS FOR HALOGEN-CONTAINING ORGANIC POLYMERS COMPRISING AN ORGANOTIN COMPOUND AND A DIESTER MORTON INTERNATIONAL, INC. (US) 1992-03-25 EP disclosed
EP-0406349-A4 IMPROVED STABILIZERS FOR HALOGEN-CONTAINING POLYMERS 1991-03-20 EP disclosed
EP-0406349-A1 IMPROVED STABILIZERS FOR HALOGEN-CONTAINING POLYMERS. M & T CHEMICALS INC (US) 1991-01-09 EP disclosed
WO-1990003999-A1 IMPROVED STABILIZERS FOR HALOGEN-CONTAINING POLYMERS M&T CHEMICALS INC. (US) 1990-04-19 WO disclosed
EP-0320147-A1 Compositions for stabilizing halogen-containing organic polymers MORTON INTERNATIONAL, INC. (US) 1989-06-14 EP disclosed
US-4839409-A ORGANOTIN OR NONTIN METAL SALTS MORTON THIOKOL, INC. (US) 1989-06-13 US disclosed
US-4834992-A Non-toxic organotin stabilizers for vinyl chloride polymers M&T CHEMICALS, INC. (US) 1989-05-30 US disclosed
EP-0070092-A1 Stabilising materials for halogen-containing polymers, polymer compositions containing the same and shaped articles formed therefrom MORTON THIOKOL, INC. (US) 1983-01-19 EP disclosed
EP-0068640-A1 Stabilising materials for halogen-containing polymers and polymer compositions containing the same MORTON THIOKOL, INC. (US) 1983-01-05 EP disclosed
US-4358555-A HEAT TESISTANCE CARSTAB CORPORATION (US) 1982-11-09 US disclosed
EP-0062406-A1 Polymer stabilising compositions, polymers stabilised therewith and shaped articles formed from such polymers MORTON THIOKOL, INC. (US) 1982-10-13 EP disclosed
US-4315850-A HEAT RESISTANT PIPES CARSTAB CORPORATION (US) 1982-02-16 US disclosed
US-4314934-A DISCOLORATION INHIBITION, HEAT RESISTANT CARSTAB CORPORATION (US) 1982-02-09 US disclosed
US-4303637-A Medication indicated for ocular hypertension ALZA CORPORATION (US) 1981-12-01 US disclosed
US-4021407-A DISCOLORATION INHIBITION CINCINNATI MILACRON, INC. (US) 1977-05-03 US disclosed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US disclosed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US disclosed