Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419137 | 0.90 | MAOB (0.64) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL20364678 | 0.85 | MAOB (0.71) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL14490205 | 0.84 | MAOB (0.69) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL669530 | 0.84 | MAOB (0.61) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL29447425 | 0.84 | MAOB (0.61) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL669531 | 0.84 | MAOB (0.61) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL11033672 | 0.83 | MAOB (0.68) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL3492356 | 0.82 | MAOB (0.60) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL16217745 | 0.82 | MAOB (0.66) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL68983 | 0.81 | MAOB (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5367079-A | Lipoxygenase inhibitors; antiinflammatory agents, antiallergens | ZENECA LIMITED (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0570112-A1 | Cycloalkane derivatives | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |