Ethylene

Ethylene

SCHEMBL9419360

C=C.CCC1CC2C=CC1C2

nearest known ligand 0.52

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.52
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HTT P42858 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ATM Q13315 1/20 0.31
GAA P10253 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109060 0.95
SCHEMBL6859763 0.85 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL28826468 0.84 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1012047 0.80 KDM4E (0.48) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL109229 0.77 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL20216336 0.77 KDM4E (0.39) KDM4EALDH1A1
SCHEMBL14344176 0.77 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AHTT
Fumaric Acid SCHEMBL11696835 0.77 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1476974 0.76
SCHEMBL4445948 0.75 KDM4E (0.48) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597119-A1 CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-18 EP disclosed