Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697977 | 1.00 | EPHX1 (0.57) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL28042955 | 1.00 | EPHX1 (0.57) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL27650515 | 1.00 | EPHX1 (0.57) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL3271036 | 1.00 | EPHX1 (0.57) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL12096491 | 0.98 | EPHX1 (0.53) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL3081607 | 0.94 | EPHX1 (0.55) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL3713923 | 0.93 | EPHX1 (0.53) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL17474391 | 0.93 | EPHX1 (0.53) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL3802705 | 0.93 | EPHX1 (0.53) | EPHX1ALDH1A1CYP1A2RAD52PPARG | |
| SCHEMBL28426490 | 0.93 | EPHX1 (0.53) | EPHX1ALDH1A1CYP1A2RAD52PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980909-B | Liquid crystal media | 默克专利股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-101053558-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2007-10-17 | — | — | CN | disclosed |
| EP-0576450-A1 | METHYLENE CYCLOBUTANE DERIVATES | MERCK PATENT GmbH (DE) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016483-A1 | METHYLENE CYCLOBUTANE DERIVATES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1992-10-01 | — | — | WO | disclosed |
| EP-0482024-A1 | CHIRAL OR ACHIRAL RING COMPOUNDS. | MERCK PATENT GMBH (DE) | 1992-04-29 | — | — | EP | disclosed |
| EP-0428665-A1 | FLUOROPHENYL PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0257049-A1 | CHIRAL COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005015-A1 | CHIRAL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |