SCHEMBL3081607

SCHEMBL3081607

CCCCCCCCCC1CCCCOO1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.55
ALDH1A1 P00352 2/20 0.48
CYP1A2 P05177 4/20 0.42
TDP1 Q9NUW8 1/20 0.38
RAD52 P43351 1/20 0.36
PPARG P37231 1/20 0.35
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
PTAFR P25105 1/20 0.33
SPHK2 Q9NRA0 1/20 0.33
SPHK1 Q9NYA1 1/20 0.33
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28180682 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL27557550 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL28847899 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL27773356 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL27434430 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL28426490 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL17474391 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL3713923 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL3802705 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52
SCHEMBL27534879 0.98 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2TDP1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282418-A9 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION Eurofarma Laboratórios S.A. (BR) 2024-07-17 EP claimed
EP-4282418-A1 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION Eurofarma Laboratórios S.A. (BR) 2023-11-29 EP claimed
WO-2022178604-A1 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION EUROFARMA LABORATORIOS S.A. (BR) 2022-09-01 WO claimed
US-20070161030-A1 Micelle-and microemulsion-assisted planar separations platform for proteomics PERKINELMER LAS, INC. 2007-07-12 US claimed
WO-2007067731-A2 MICELLE- AND MICROEMULSION-ASSISTED PLANAR SEPARATIONS PLATFORM FOR PROTEOMICS PERKINELMER LAS, INC. (US) 2007-06-14 WO claimed
EP-4282418-A9 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION Eurofarma Laboratórios S.A. (BR) 2024-07-17 EP disclosed
EP-4282418-A1 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION Eurofarma Laboratórios S.A. (BR) 2023-11-29 EP disclosed
WO-2022178604-A1 FOAMING TOPICAL PHARMACEUTICAL COMPOSITION EUROFARMA LABORATORIOS S.A. (BR) 2022-09-01 WO disclosed
US-20220184038-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES SISAF LIMITED (GB) 2022-06-16 US disclosed
EP-3946279-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES Sisaf Ltd (GB) 2022-02-09 EP disclosed
WO-2020193998-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES SISAF LIMITED (GB) 2020-10-01 WO disclosed
EP-3714879-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES Sisaf Ltd (GB) 2020-09-30 EP disclosed
EP-1913390-A2 ASSAY PARTICLES AND METHODS OF USE PerkinElmer LAS, Inc. (US) 2008-04-23 EP disclosed
EP-1774276-A4 METHODS AND COMPOSITIONS FOR DETECTING AND ISOLATING PHOSPHORYLATED MOLECULES USING HYDRATED METAL OXIDES PERKINELMER LAS INC (US) 2007-08-29 EP disclosed
US-20070161030-A1 Micelle-and microemulsion-assisted planar separations platform for proteomics PERKINELMER LAS, INC. 2007-07-12 US disclosed
WO-2007067731-A2 MICELLE- AND MICROEMULSION-ASSISTED PLANAR SEPARATIONS PLATFORM FOR PROTEOMICS PERKINELMER LAS, INC. (US) 2007-06-14 WO disclosed
EP-1774276-A2 METHODS AND COMPOSITIONS FOR DETECTING AND ISOLATING PHOSPHORYLATED MOLECULES USING HYDRATED METAL OXIDES Perkinelmer Las, Inc. (US) 2007-04-18 EP disclosed
WO-2007022074-A2 ASSAY PARTICLES AND METHODS OF USE PERKINELMER LAS, INC. (US) 2007-02-22 WO disclosed
US-20070037215-A1 Assay particles and methods of use PERKINELMER LAS, INC. 2007-02-15 US disclosed
WO-2006014424-A2 METHODS AND COMPOSITIONS FOR DETECTING AND ISOLATING PHOSPHORYLATED MOLECULES USING HYDRATED METAL OXIDES PERKINELMER LAS, INC. (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220184038-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES SGMS1, SGMS2, SMURF1 EPHX1 1527/4885ALDH1A1 4855/4885CYP1A2 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.