SCHEMBL9419488

SCHEMBL9419488

CC=C(C)[SiH2]O[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701460 0.85 MAPT (0.35) MAPTESR1ESR2
SCHEMBL1679728 0.83 MAPT (0.36) MAPTESR1ESR2
SCHEMBL2135202 0.83 MAPT (0.36) MAPTESR1ESR2
SCHEMBL9419490 0.74 MAPT (0.32) MAPTESR1ESR2
SCHEMBL6157102 0.71 ESR1 (0.32) ESR1ESR2
SCHEMBL11577913 0.70 NR1H2 (0.32) ESR1ESR2
SCHEMBL1599649 0.68 MAPT (0.39) MAPTESR1ESR2
SCHEMBL5701337 0.68
SCHEMBL10546497 0.67 MAPT (0.42) MAPTESR1ESR2
SCHEMBL3795357 0.66 ESR1 (0.39) MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5364896-A Plasticizers for silicone rubbers DOW CORNING TORAY SILICONE CO., LTD (JP) 1994-11-15 US disclosed
EP-0544257-A2 Triorganosiloxydiphenylsilanols and method for preparing same Dow Corning Toray Silicone Company, Limited (JP) 1993-06-02 EP disclosed