Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157102 | 0.79 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL3967327 | 0.74 | — | — | |
| SCHEMBL11577908 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL688585 | 0.72 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL27587595 | 0.70 | ESR1 (0.36) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL9419490 | 0.70 | MAPT (0.32) | ESR1ESR2 | |
| SCHEMBL9419488 | 0.70 | MAPT (0.35) | ESR1ESR2 | |
| SCHEMBL2678713 | 0.69 | ESR1 (0.33) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL3795357 | 0.69 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2 | |
| Methane SCHEMBL11653540 | 0.67 | ESR1 (0.33) | NR1H2NR1H3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180291299-A1 | ORGANOSILOXANE COMPOSITIONS | DOW SILICONES CORP (US) | 2018-10-11 | — | — | US | disclosed |
| US-10011801-B2 | Organosiloxane compositions | DOW SILICONES CORPORATION (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160281019-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION | 2016-09-29 | — | — | US | disclosed |
| EP-3071678-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077391-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2015-05-28 | — | — | WO | disclosed |
| US-4075169-A | Fluorosiloxydiphenylsiloxy block copolymers | GENERAL ELECTRIC COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4028338-A | SOLVENT RESISTANT | GENERAL ELECTRIC COMPANY (US) | 1977-06-07 | — | — | US | disclosed |