Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Oxide SCHEMBL2313685 | 0.90 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27851159 | 0.85 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7642504 | 0.83 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methyl Alcohol SCHEMBL28276837 | 0.82 | TSHR (0.91) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21630258 | 0.82 | TSHR (1.00) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL30363554 | 0.82 | TSHR (1.00) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14875 | 0.82 | — | — | |
| SCHEMBL3356310 | 0.81 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| Oxirane SCHEMBL6686130 | 0.81 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL660331 | 0.81 | TSHR (0.86) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670512-A | ADDUCT OF ALKYLENE OXIDE AND A HYDROXYALKYL (METH)ACRYLATE AND COPOLYMERIZABLE MONOMER | THE DOW CHEMICAL COMPANY (US) | 1987-06-02 | — | — | US | claimed |
| EP-0354034-B1 | Resin composition | TORAY INDUSTRIES (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5047475-A | Automobile trims; exteriors of electrical appliances | TORAY INDUSTRIES, INC. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0354034-A2 | Resin composition | TORAY INDUSTRIES, INC. (JP) | 1990-02-07 | — | — | EP | disclosed |
| US-4126527-A | IN ADMIXTURE WITH POLYACRYLATE | MOBIL OIL CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |