Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097385 | 1.00 | MAPK1 (0.65) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL10536163 | 1.00 | MAPK1 (0.65) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11230329 | 0.98 | KDM4E (0.63) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL12515200 | 0.94 | KDM4E (0.63) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL1852359 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11618437 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11139136 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11617865 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11611741 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL11614197 | 0.91 | L3MBTL1 (0.73) | MAPK1KDM4EMAPTHIF1ASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371288-A | Branched alkyl-containing aminobenzamides as chain extenders in polyurethane-urea elastomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-12-06 | — | — | US | disclosed |