Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420352 | 0.81 | MAPT (0.45) | ALDH1A1LMNAPKMKMT2AKDM4E | |
| SCHEMBL9420356 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAPKMKMT2AKDM4E | |
| SCHEMBL9420341 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNAPKMKMT2AKDM4E | |
| SCHEMBL9420340 | 0.79 | MAPK10 (0.50) | ALDH1A1KDM4EHSD17B10PTGS1MAPT | |
| SCHEMBL9420350 | 0.79 | MAPK10 (0.50) | ALDH1A1KDM4EHSD17B10PTGS1MAPT | |
| SCHEMBL9420328 | 0.79 | MAPK10 (0.50) | ALDH1A1KDM4EHSD17B10PTGS1MAPT | |
| SCHEMBL9420353 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL9420325 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAKMT2AKDM4EMPO | |
| SCHEMBL9420345 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAKMT2AKDM4EMPO | |
| SCHEMBL9420364 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354179-B1 | Thiouracils as stabilizers for polymers containing chlorine | CIBA GEIGY AG (CH) | 1994-08-17 | — | — | EP | claimed |
| EP-0354179-B1 | Thiouracils as stabilizers for polymers containing chlorine | CIBA GEIGY AG (CH) | 1994-08-17 | — | — | EP | disclosed |
| EP-0354179-A1 | Thiouracils as stabilizers for polymers containing chlorine | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |