⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385705 | 0.88 | — | — | |
| SCHEMBL9420425 | 0.80 | TSHR (0.37) | — | |
| SCHEMBL3382553 | 0.80 | — | — | |
| SCHEMBL1795078 | 0.79 | — | — | |
| SCHEMBL3384620 | 0.79 | — | — | |
| SCHEMBL3383733 | 0.75 | THRB (0.37) | — | |
| SCHEMBL1792811 | 0.74 | — | — | |
| SCHEMBL301449 | 0.70 | USP2 (0.31) | — | |
| SCHEMBL9420433 | 0.70 | THRB (0.39) | — | |
| SCHEMBL3382093 | 0.69 | THRB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295821-B1 | Method for production of graft resin composition | NIPPON OILS & FATS CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4839423-A | USING A UNSATURATED ORGANIC PEROXY FREE RADICAL CATALYSY | NIPPON OIL & FATS CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0295821-A2 | Method for production of graft resin composition | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-12-21 | — | — | EP | disclosed |