Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420625 | 0.96 | CYP3A4 (0.41) | CYP3A4TSHRCYP1A2 | |
| SCHEMBL9420514 | 0.80 | SERPINE1 (0.49) | CYP3A4TSHRSERPINE1CYP1A2 | |
| SCHEMBL9420474 | 0.80 | SERPINE1 (0.49) | CYP3A4TSHRSERPINE1CYP1A2 | |
| SCHEMBL9420499 | 0.80 | SERPINE1 (0.49) | CYP3A4TSHRSERPINE1CYP1A2 | |
| SCHEMBL15375181 | 0.77 | CYP4F2 (0.40) | CYP3A4TSHRSERPINE1 | |
| SCHEMBL10524809 | 0.77 | CYP3A4 (0.35) | CYP3A4TSHR | |
| SCHEMBL10524815 | 0.75 | SERPINE1 (0.44) | CYP3A4TSHRSERPINE1CYP1A2 | |
| SCHEMBL813539 | 0.75 | TSHR (0.47) | CYP3A4TSHRSERPINE1CYP1A2 | |
| SCHEMBL16262350 | 0.74 | GAA (0.46) | CYP3A4TSHRCYP1A2 | |
| SCHEMBL13611328 | 0.74 | SERPINE1 (0.40) | CYP3A4TSHRSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |