Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420477 | 1.00 | TSHR (0.44) | TSHRCES1CA1CA2TDP1 | |
| SCHEMBL9420552 | 0.97 | TSHR (0.46) | TSHRCES1CA1CA2TDP1 | |
| SCHEMBL9420540 | 0.85 | TSHR (0.49) | TSHRCES1LMNAALDH1A1MEN1 | |
| SCHEMBL9420557 | 0.82 | ALDH1A1 (0.47) | TSHRTDP1LMNAALDH1A1MAPK1 | |
| SCHEMBL9420487 | 0.80 | APP (0.43) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL9420508 | 0.80 | APP (0.43) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL18393364 | 0.80 | SMN1; SMN2 (0.42) | TSHRCES1TDP1LMNAGAA | |
| Tetraethylene Glycol SCHEMBL11369985 | 0.80 | TDP1 (0.68) | TSHRCES1CA1CA2TDP1 | |
| 4-Nitrobenzoic Acid SCHEMBL11366971 | 0.80 | TDP1 (0.68) | TSHRCES1CA1CA2TDP1 | |
| SCHEMBL9733853 | 0.79 | CES1 (0.49) | TSHRCES1CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |