Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422010 | 1.00 | KMT2A (0.40) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL9422033 | 0.95 | KMT2A (0.40) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| Tetramethylammonium Ion SCHEMBL9422036 | 0.95 | KMT2A (0.40) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11577481 | 0.94 | CYP1B1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11580149 | 0.94 | MAPK1 (0.42) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11577483 | 0.94 | CYP1B1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11580347 | 0.94 | MAPK1 (0.42) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11577477 | 0.94 | CYP1B1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11580342 | 0.94 | MAPK1 (0.42) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11580434 | 0.93 | RAB9A (0.41) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340804-A | In vertebrate animals | ELI LILLY AND COMPANY (US) | 1994-08-23 | — | — | US | claimed |
| EP-0546687-A2 | Formazan parasiticides | ELI LILLY AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| US-4069320-A | Substituted diphenyl-3-formazancarbonitrile insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-01-17 | — | — | US | claimed |
| JP-5239010-A | — | — | None | — | — | JP | disclosed |
| US-5340804-A | In vertebrate animals | ELI LILLY AND COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| JP-H05239010-A | FORMAZAN PARASITICIDE | ELI LILLY & CO | 1993-09-17 | — | — | JP | disclosed |
| EP-0546687-A2 | Formazan parasiticides | ELI LILLY AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4098831-A | NITROBENZOTRICHLORIDE OR BROMIDE PROCESS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4069320-A | Substituted diphenyl-3-formazancarbonitrile insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-4069320-A | Substituted diphenyl-3-formazancarbonitrile insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-3993704-A | Para-nitrobenzotribromide process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3993704-A | Para-nitrobenzotribromide process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-23 | — | — | US | disclosed |