Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218375 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL14149371 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL8367769 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL13924928 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL18991574 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL13970293 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL6899575 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL3450290 | 0.97 | SMPD1 (0.45) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL8370603 | 0.95 | FDPS (0.43) | SMPD1FDPSDNM1TSHRTHRB | |
| SCHEMBL11608628 | 0.89 | SMPD1 (0.34) | SMPD1FDPSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290676-B1 | Improved disinfectant polymeric coatings for hard surfaces | ECOLAB INC (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0290739-B1 | IMPROVED DISINFECTANT POLYMERIC COATINGS FOR HARD SURFACES | ECOLAB INC. (US) | 1993-02-10 | — | — | EP | disclosed |
| US-5154920-A | Adherent, water-resistant | ECOLAB INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0233088-B1 | COMPOSITION AND PROCESS FOR BONDING A FLUTED FILTER MEDIUM TO AN END CAP THEREFOR | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| US-5061485-A | Film forming acrylic polymer | ECOLAB INC. (US) | 1991-10-29 | — | — | US | disclosed |
| EP-0194770-B1 | DISINFECTANT POLYMERIC COATINGS FOR HARD SURFACES | ECOLAB INC. (US) | 1991-07-17 | — | — | EP | disclosed |
| EP-0260797-B1 | BOOK BINDING PROCESS INVOLVING PRIMER ADHESIVE CONTAINING STARCH | H.B. FULLER COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4999386-A | Germicidal agent contained in polymer film, sustained release | ECOLAB INC. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4890444-A | Bonded fluted filter media to end cap | H. B. FULLER COMPANY (US) | 1990-01-02 | — | — | US | disclosed |
| US-4883828-A | Disinfectant polymeric coatings for hard surfaces | ECOLAB INC. (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0290739-A2 | Improved disinfectant polymeric coatings for hard surfaces | ECOLAB INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| EP-0290676-A2 | Improved disinfectant polymeric coatings for hard surfaces | ECOLAB INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4769096-A | Process of bonding fluted filter media to end caps | H.B. FULLER COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0260797-A2 | Book binding process involving primer adhesive containing starch | H.B. FULLER COMPANY (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4702496-A | Book binding process involving primer adhesive containing starch | H. B. FULLER COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| US-4690821-A | HYDROPHILIC AND HYDROPHOBIC EMOLLIENT OILS, ETHYLENE OXIDE ADDUCTS, FATTY ACID ESTERS, PROPYLENE OXIDE ADDUCTS, POLYETHERS | CREATIVE PRODUCTS RESOURCE ASSOCIATES, LTD. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0233088-A2 | Composition and process for bonding a fluted filter medium to an end cap therefor | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1987-08-19 | — | — | EP | disclosed |
| EP-0194770-A2 | Disinfectant polymeric coatings for hard surfaces | ECOLAB INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0161936-A2 | Book binding process | H.B. FULLER COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |
| US-4536012-A | COATING SPINE WITH ADHESIVE LATEX AND STARCH; EVAPORATION TO FORM FLEXIBLE, TACKY FILM | H. B. FULLER COMPANY (US) | 1985-08-20 | — | — | US | disclosed |