Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.69 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.55 |
| ▸ | RBP4 | P02753 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665105 | 0.92 | HRH4 (0.72) | HRH4PDE10ARBP4PARP1DRD3 | |
| SCHEMBL22718876 | 0.91 | HRH4 (0.76) | HRH4PDE10ARBP4DRD3 | |
| Hydrochloric Acid SCHEMBL2238748 | 0.90 | HRH4 (0.71) | HRH4PDE10ARBP4PARP1DRD3 | |
| SCHEMBL9832108 | 0.90 | HRH4 (0.74) | HRH4PDE10ARBP4DRD3 | |
| SCHEMBL30358191 | 0.90 | HRH4 (0.74) | HRH4PDE10ARBP4DRD3 | |
| SCHEMBL602036 | 0.83 | HRH4 (0.90) | HRH4PDE10ADRD3 | |
| SCHEMBL18889258 | 0.82 | ALDH1A1 (0.72) | HRH4PDE10ARBP4 | |
| SCHEMBL604426 | 0.82 | HRH4 (1.00) | HRH4PDE10ARBP4DRD3 | |
| SCHEMBL602694 | 0.79 | HRH4 (0.63) | HRH4PDE10ARBP4 | |
| SCHEMBL20827228 | 0.78 | HRH4 (0.66) | HRH4PDE10ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6329641-A | — | — | None | — | — | JP | disclosed |
| JP-H06329641-A | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1994-11-29 | — | — | JP | disclosed |