Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261832 | 0.85 | TRPA1 (0.50) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL9556774 | 0.84 | TRPA1 (0.49) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL9198461 | 0.80 | TRPA1 (0.54) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL9519785 | 0.80 | TRPA1 (0.54) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL4328080 | 0.80 | TRPA1 (0.61) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL4322717 | 0.79 | TRPA1 (0.50) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL755804 | 0.78 | GAA (0.64) | GAACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11519193 | 0.78 | TRPA1 (0.52) | GAATRPA1GSRGABRA1GABRB1 | |
| SCHEMBL9422303 | 0.77 | MEN1 (0.48) | GAATRPA1KMT2A | |
| SCHEMBL9625369 | 0.76 | GAA (0.74) | GAACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382559-B1 | Polymer composition | TONEN SEKIYUKAGAKU KK (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5216054-A | Polyamide, polyolefin, carboxylic acid modified polyolefin, substituted hydrazine, hindered phenol, phosphite, thiodipropionate; aging resistance and resistance to copper-caused deterioration | TONEN SEKIYUKAGAKU KABUSHIKI KAISHA (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0382559-A2 | Polymer composition | Tonen Chemical Corporation (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |