Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125838 | 0.82 | KDM4E (0.35) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8210030 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777005 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9575551 | 0.77 | KDM4E (0.30) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3158156 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8205815 | 0.73 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019861 | 0.73 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777016 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL965011 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9019744 | 0.72 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6056834-A | — | — | None | — | — | JP | disclosed |
| JP-H0656834-A | CARBOXYLIC ACID ESTER OF 2-AMINO-7-((1,3-DIHYDROXY-2-PROPOXY) METHYL)PURINE, ITS PREPARATION AND ITS USE | HOECHST AG | 1994-03-01 | — | — | JP | disclosed |