Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125195 | 0.80 | ALOX5AP (0.60) | ALOX5 | |
| SCHEMBL9122807 | 0.80 | ALOX5AP (0.60) | ALOX5 | |
| SCHEMBL9123925 | 0.80 | ALOX5AP (0.60) | ALOX5 | |
| SCHEMBL1745498 | 0.78 | MAPT (0.61) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7544973 | 0.75 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9564275 | 0.75 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9422612 | 0.75 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7541535 | 0.74 | ALDH1A1 (0.80) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8921057 | 0.74 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7542600 | 0.74 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6065214-A | — | — | None | — | — | JP | disclosed |
| JP-H0665214-A | SUBSTITUTED (BENZOTHIAZOLYL-AND QUINOXALYL-METHOXY) PHENYL-ACETIC ACID DERIVATIVES | BAYER AG | 1994-03-08 | — | — | JP | disclosed |