SCHEMBL942278

SCHEMBL942278

[O][C@H]1CCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL939613 1.00
SCHEMBL4356389 1.00
SCHEMBL37819 1.00
SCHEMBL591561 0.81
SCHEMBL302739 0.81
SCHEMBL11516730 0.81
SCHEMBL524702 0.79
SCHEMBL302385 0.79
SCHEMBL4350655 0.74 ATF4 (0.30)
SCHEMBL28143526 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376830-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF RENAL DISEASES IN NON-HUMAN MAMMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
CN-117715639-A Use of SGLT-2 inhibitors for the prevention and/or treatment of kidney disease in non-human mammals 勃林格殷格翰动物保健有限公司 2024-03-15 CN claimed
CN-117715640-A Use of SGLT-2 inhibitors for preventing and/or treating heart diseases in non-human mammals excluding felines, particularly canines 勃林格殷格翰动物保健有限公司 2024-03-15 CN claimed
US-20240050456-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREAT-MENT OF CARDIAC DISEASES IN FELINES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-02-15 US claimed
WO-2023227492-A1 AQUEOUS PHARMACEUTICAL COMPOSITIONS COMPRISING SGLT-2 INHIBITORS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-11-30 WO claimed
US-20230381101-A1 AQUEOUS PHARMACEUTICAL COMPOSITIONS COMPRISING SGLT-2 INHIBITORS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-11-30 US claimed
US-20230338406-A1 USE OF SGLT-2 INHIBITORS IN THE DRYING-OFF OF NON-HUMAN MAMMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-10-26 US claimed
EP-3862003-B1 AN SGLT-2 INHIBITOR FOR USE IN THE TREATMENT OF A METABOLIC DISORDER IN FELINE ANIMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-10-25 EP claimed
EP-4245765-A2 TREATMENT OF METABOLIC DISORDERS IN EQUINE ANIMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2023-09-20 EP claimed
US-11759474-B2 Use of SGLT-2 inhibitors in the drying-off of non-human mammals BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-09-19 US claimed
US-20110237532-A1 1-[(3-CYANO-PYRIDIN-2-YL)METHYL]-3-METHYL-7-(2-BUTYN-1-YL)-8-[3-(R)-AMINO-PIPERIDIN-1-YL]-XANTHINE FOR THE TREATMENT OF A METABOLIC DISORDER OF A PREDOMINANTLY CARNIVOROUS NON-HUMAN ANIMAL BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2011-09-29 US claimed
EP-2368552-A1 1-[(3-cyano-pyridin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[3-(r)-amino-piperidin-1-yl]-xanthine for the treatment of a metabolic disorder of a predominantly carnivorous non-human animal Boehringer Ingelheim Vetmedica GmbH (DE) 2011-09-28 EP claimed
US-20110195917-A1 PHARMACEUTICAL COMPOSITION COMPRISING A GLUCOPYRANOSYL-SUBSTITUTED BENZENE DERIVATE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-11 US claimed
US-20110046087-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-02-24 US claimed
US-20110046076-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-02-24 US claimed
US-20100209506-A1 PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL DOSAGE FORM, PROCESS FOR THEIR PREPARATION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-08-19 US claimed
US-20100179191-A1 GLUCOPYRANOSYL-SUBSTITUTED CYCLOPROPYLBENZENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AS SGLT INHIBITORS AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-07-15 US claimed
EP-2054426-A1 GLUCOPYRANOSYL-SUBSTITUTED CYCLOPROPYLBENZENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AS SGLT INHIBITORS AND PROCESS FOR THEIR MANUFACTURE Boehringer Ingelheim International GmbH (DE) 2009-05-06 EP claimed
US-20080058379-A1 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-03-06 US claimed
WO-2008020011-A1 GLUCOPYRANOSYL-SUBSTITUTED CYCLOPROPYLBENZENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AS SGLT INHIBITORS AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-02-21 WO claimed