Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423251 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423405 | 0.78 | SETDB1 (0.42) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9395502 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423391 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423493 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423502 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423485 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423486 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423620 | 0.72 | CYP19A1 (0.47) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL9423298 | 0.71 | KDM4E (0.41) | ALDH1A1TSHRKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318971-A | Also antihyperproliferative skin disease agents, e.g. psoriaisis; side effect reduction | SCHERING CORPORATION (US) | 1994-06-07 | — | — | US | claimed |
| US-5318971-A | Also antihyperproliferative skin disease agents, e.g. psoriaisis; side effect reduction | SCHERING CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-5064837-A | Antiallergens | SCHERING CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |