Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233017 | 0.98 | ALDH1A1 (0.41) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL10088355 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL20915220 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL4521504 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL16837384 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL2703075 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL11933712 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL13519918 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL11933713 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT | |
| SCHEMBL1148287 | 0.96 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDGPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332820-A | Diuretic, hypotensive agent, treating congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |