Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911 | 0.85 | HTT (0.45) | MAPTHTTHIF1AARTSHR | |
| SCHEMBL7603042 | 0.84 | NR1H4 (0.36) | NPC1RAB9AMAPTHTTHIF1A | |
| SCHEMBL11303015 | 0.82 | TSHR (0.46) | MAPTHIF1ATSHRSMN1; SMN2LMNA | |
| SCHEMBL7068885 | 0.82 | HTT (0.33) | NPC1RAB9AMAPTHTTHIF1A | |
| SCHEMBL12897836 | 0.79 | HTT (0.41) | NPC1RAB9AMAPTHTTHIF1A | |
| SCHEMBL12050062 | 0.79 | ESR1 (0.53) | HTTHIF1AARTSHRLMNA | |
| SCHEMBL9615448 | 0.77 | ESR1 (0.42) | NPC1RAB9AHTTTSHRSMN1; SMN2 | |
| SCHEMBL11656586 | 0.77 | SMN1; SMN2 (0.34) | MAPTHTTNR1H4SMN1; SMN2LMNA | |
| SCHEMBL8674766 | 0.77 | MAPT (0.44) | MAPTTSHRCYP2C9ESR2PTPN5 | |
| SCHEMBL24747124 | 0.76 | ESR1 (0.44) | NR1H4ARTSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322752-A | Development process for abrasion resistant documents | XEROX CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| US-4672018-A | Flash fusing process with prespheroidized toner | XEROX CORPORATION (US) | 1987-06-09 | — | — | US | disclosed |
| US-4634649-A | Developer compositions | XEROX CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| US-4520092-A | Process for preventing deposition of toner particles in an imaging apparatus | XEROX CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |