Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761082 | 0.85 | ESR1 (0.66) | ESR1ESR2NR1H4PTPN5KMT2A | |
| SCHEMBL24815727 | 0.83 | NR1H4 (0.40) | NR1H4PTPN5KMT2ACYP3A4MEN1 | |
| SCHEMBL12805064 | 0.82 | LTA4H (0.55) | ESR1ESR2KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL12541779 | 0.82 | ESR1 (0.53) | ESR1ESR2NR1H4PTPN5KMT2A | |
| SCHEMBL8636388 | 0.82 | ESR1 (0.61) | ESR1ESR2NR1H4PTPN5KMT2A | |
| SCHEMBL68287 | 0.82 | ESR1 (0.62) | ESR1ESR2KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7603042 | 0.81 | NR1H4 (0.36) | ESR1ESR2NR1H4PTPN5KMT2A | |
| SCHEMBL8760898 | 0.81 | ESR2 (0.53) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| Methyl Alcohol SCHEMBL28148921 | 0.80 | ESR1 (0.60) | ESR1ESR2KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL28485 | 0.80 | KMT2A (0.56) | ESR1ESR2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220397835-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2022-12-15 | — | — | US | disclosed |