Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.62 |
| ▸ | PNP | P00491 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503470 | 1.00 | PDE4D (0.62) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL29319896 | 0.88 | PDE4D (0.62) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL7140801 | 0.83 | AHCY (0.52) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL7140807 | 0.83 | AHCY (0.52) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL7097329 | 0.83 | AHCY (0.52) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL19503474 | 0.83 | AHCY (0.49) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL12157236 | 0.81 | AHCY (0.66) | ADORA3ADORA2AADORA1AHCY | |
| SCHEMBL9687054 | 0.81 | AHCY (0.66) | ADORA3ADORA2AADORA1AHCY | |
| SCHEMBL12173989 | 0.81 | AHCY (0.66) | ADORA3ADORA2AADORA1AHCY | |
| SCHEMBL9310338 | 0.81 | AHCY (0.70) | PDE4DPDE3APNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332814-A | Process for the preparation of carbacyclic nucleosides, and intermediates | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0542681-A1 | Process for the preparation of carbocyclic nucleosides and its intermediates | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |