Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962426 | 0.87 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13470760 | 0.85 | ALDH1A1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL153056 | 0.82 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21101774 | 0.82 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27655956 | 0.82 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8078511 | 0.82 | KDM4E (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28830235 | 0.81 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6700957 | 0.79 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3225432 | 0.79 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16011227 | 0.78 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536475-B | Polyglyoxylic acid esters, their preparation and use | 西安大略大学 | 2021-04-30 | — | — | CN | disclosed |
| US-5356914-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0552213-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1993-07-28 | — | — | EP | disclosed |
| US-5231107-A | Compounds for treatment of Alzheimer*s disease or memory defects | ROUSSEL UCLAF (FR) | 1993-07-27 | — | — | US | disclosed |
| WO-1992006959-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
| US-4921868-A | Carbamate derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1990-05-01 | — | — | US | disclosed |