SCHEMBL9424067

SCHEMBL9424067

O=C(O)CCCCOc1ccc2oc3ccccc3c(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACSL1 P33121 3/20 1.00
ACSL6 Q9UKU0 2/20 1.00
MAOB P27338 6/20 0.60
HRH3 Q9Y5N1 6/20 0.60
BCHE P06276 6/20 0.60
ACHE P22303 4/20 0.60
LMNA P02545 1/20 0.59
NPC1 O15118 1/20 0.58
POLB P06746 1/20 0.58
RAB9A P51151 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TTR P02766 1/20 0.56
MAOA P21397 1/20 0.56
ALK Q9UM73 1/20 0.55
XDH P47989 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24634625 0.99 ACSL1 (1.00) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL27256204 0.89 ACSL1 (0.80) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL27256205 0.88 ACSL1 (0.80) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL7812629 0.87 ACSL1 (0.77) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL22730029 0.85 ACSL1 (0.77) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL9424000 0.85 ACSL1 (0.73) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL1247012 0.84 LMNA (0.82) ACSL1ACSL6MAOBHRH3LMNA
SCHEMBL5030900 0.83 ACSL1 (0.70) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL20594363 0.82 ACSL1 (0.72) ACSL1ACSL6MAOBHRH3BCHE
SCHEMBL20594883 0.82 ACSL1 (0.72) ACSL1ACSL6MAOBHRH3BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022212568-A9 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM 1BASE PHARMACEUTICALS, LLC (US) 2023-11-16 WO disclosed
WO-2022212568-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM 1BASE PHARMACEUTICALS, LLC (US) 2022-10-06 WO disclosed
US-5306562-A Xanthenylamide handle for use in peptide synthesis REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1994-04-26 US disclosed
US-5117009-A XANTHENYLAMIDE HANDLE FOR USE IN PEPTIDE SYNTHESIS UNIVERSITY OF MINNESOTA (US) 1992-05-26 US disclosed
EP-0473411-A1 Xanthenylamide handle for use in peptide synthesis and methods of producing said handle and support incorporating it REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-03-04 EP disclosed