Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424147 | 1.00 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL10441828 | 0.91 | AGTR1 (0.66) | AGTR1 | |
| SCHEMBL6960438 | 0.89 | AGTR1 (0.77) | AGTR1 | |
| SCHEMBL6960441 | 0.89 | AGTR1 (0.77) | AGTR1 | |
| SCHEMBL9424171 | 0.86 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9424168 | 0.86 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9424134 | 0.85 | AGTR1 (0.66) | AGTR1 | |
| SCHEMBL9424128 | 0.85 | AGTR1 (0.66) | AGTR1 | |
| SCHEMBL9424073 | 0.85 | — | — | |
| SCHEMBL9424075 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |