Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.68 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.68 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424588 | 1.00 | AGTR1 (0.68) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7051753 | 0.94 | AGTR1 (0.77) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7446920 | 0.94 | AGTR1 (0.77) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424465 | 0.92 | AGTR1 (0.72) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424461 | 0.92 | AGTR1 (0.72) | AGTR1ABCC3ABCC2 | |
| SCHEMBL682660 | 0.87 | AGTR1 (0.90) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6959040 | 0.87 | AGTR1 (0.90) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424499 | 0.86 | AGTR1 (0.68) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424507 | 0.86 | AGTR1 (0.68) | AGTR1ABCC3ABCC2 | |
| SCHEMBL682668 | 0.86 | AGTR1 (0.75) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |