Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313557 | 0.88 | TSHR (0.50) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL9425753 | 0.80 | TSHR (0.44) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL9425543 | 0.77 | TSHR (0.42) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL503651 | 0.76 | SMN1; SMN2 (0.70) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL17229449 | 0.75 | SMN1; SMN2 (0.41) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL12636212 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL8827471 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL3026303 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL4920850 | 0.74 | TSHR (0.47) | TSHRSMN1; SMN2MAPTPOLBTDP1 | |
| SCHEMBL3216951 | 0.71 | MAPT (0.50) | TSHRSMN1; SMN2MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360819-A | Nonradioactive labels which provide a ketone signal, vapor phase analysis | NORTHEASTERN UNIVERSITY (US) | 1994-11-01 | — | — | US | disclosed |